Work Your Magic with us!
Ready to explore, break barriers, and discover more? We know you've got big plans - so do we! Our colleagues across the globe love innovating with science and technology to enrich people's lives with our solutions in Healthcare, Life Science, and Electronics. Together, we dream big and are passionate about caring for our rich mix of people, customers, patients, and planet. That's why we are always looking for curious minds that see themselves imagining the unimaginable with us.
United As One for Patients, our purpose in Healthcare is to help create, improve and prolong lives. We develop medicines, intelligent devices and innovative technologies in therapeutic areas such as Oncology, Neurology and Fertility. Our teams work together across 6 continents with passion and relentless curiosity in order to help patients at every stage of life. Joining our Healthcare team is becoming part of a diverse, inclusive and flexible working culture, presenting great opportunities for personal development and career advancement across the globe.
Your role:
As the Associate Scientific Director in Translational Quantitative Pharmacology, you will play a pivotal role in shaping Model Informed Drug Development (MIDD) strategies throughout the R&D lifecycle. You will be responsible for all TQP assignments either executed internally or in collaboration with external TQP related CROs by providing close scientific and technical supervision. You will be expected to manage multiple projects simultaneously and participate in discussions and presentations. You will be responsible for developing quantitative mechanism-based PK/PD models that inform critical decisions from lead optimization to clinical proof of concept, particularly within the immunology and oncology pipelines. Your role will also involve performing human PK predictions and designing pre-clinical PK/PD experiments to support development efforts. You will interact with project team members, communicate results of model-based analyses and foster a collaborative environment. By implementing innovative modeling and simulation platforms, you will ensure that the right drug is administered to the right patient at the right dosage. Your contributions will extend to preparing and presenting documentation for internal and external stakeholders, enhancing our program strategy and impact.
Who you are:

  • You have a minimum of 5 years of experience in industry and/or academia in a relevant field.
  • You hold a PhD in Pharmacokinetics, Pharmaceutical Sciences, Biomedical/Chemical Engineering, Applied Mathematics, or a related discipline, demonstrating a proven track record in modeling and simulation.
  • You are fluent in English and possess sound knowledge of Quantitative Systems Pharmacology principles.
  • You have hands-on experience in mathematical modeling of pharmacologic effects with mechanism-based models using software such as MATLAB/SimBiology, NONMEM, or R.
  • You have applied translational PK/PD modeling and simulation, including QSP models, in research and early clinical development.
  • You understand the basic principles of biology and pharmacology, particularly in oncology, immunology, or immuno-oncology.
  • You are capable of rapidly assimilating complex biological knowledge and transforming it into multi-scale mathematical models.
  • You possess excellent communication skills, enabling you to translate modeling outcomes effectively for research and development projects.

What we offer:
We are curious minds that come from a broad range of backgrounds, perspectives, and life experiences. We believe that this variety drives excellence and innovation, strengthening our ability to lead in science and technology. We are committed to creating access and opportunities for all to develop and grow at your own pace. Join us in building a culture of inclusion and belonging that impacts millions and empowers everyone to work their magic and champion human progress!
Apply now and become a part of a team that is dedicated to Sparking Discovery and Elevating Humanity!

Merck

Merck

Merck

Möchten Sie sich auf diese Stelle bewerben, klicken Sie auf den nachfolgenden Button

Job Overview
  • Verfügbar ab

    27.09.2025

  • Besucher

    1,560 Besuche

  • Anzahl

    1 Freie Stelle

  • Verfügbar bis

    27.12.2025

  • Arbeitsort

    64283 Darmstadt

  • Schulbildung

    Branchenspezifisch

  • Kategorie

    Sonstige

Kontakt Info
64283 Darmstadt

Weitere Jobs der Firma Merck in der

Work Your Magic with us Ready to explore, break barriers, and discover more We know you ve got big plans - so do we Our colleagues across the globe love innovating with science and technology to enrich people s lives with our solutions in Healthcare, Life Science, and Electronics. ...
Job anzeigen
Merck
  • Sonstige
  • 27.09.2025
  • 64283 Darmstadt
Work Your Magic with us Ready to explore, break barriers, and discover more We know you ve got big plans - so do we Our colleagues across the globe love innovating with science and technology to enrich people s lives with our solutions in Healthcare, Life Science, and Electronics. ...
Job anzeigen
Entfalte das Besondere mit uns Sind Sie bereit, neue Wege zu gehen, Herausforderungen zu meistern und Neues zu entdecken Wir wissen, dass Sie große Pläne haben - und die haben wir auch Unsere Kolleg innen auf der ganzen Welt lieben es, mit Wissenschaft und Technologie innovativ zu sein ...
Job anzeigen
Merck
  • Handwerk
  • 26.09.2025
  • 64283 Darmstadt
Entfalte das Besondere mit uns Sind Sie bereit, neue Wege zu gehen, Herausforderungen zu meistern und Neues zu entdecken Wir wissen, dass Sie große Pläne haben - und die haben wir auch Unsere Kolleg innen auf der ganzen Welt lieben es, mit Wissenschaft und Technologie innovativ zu sein ...
Job anzeigen
Merck
  • Sonstige
  • 26.09.2025
  • 64283 Darmstadt
Work Your Magic with us Ready to explore, break barriers, and discover more We know you ve got big plans - so do we Our colleagues across the globe love innovating with science and technology to enrich people s lives with our solutions in Healthcare, Life Science, and Electronics. ...
Job anzeigen
Merck
  • Sonstige
  • 26.09.2025
  • 64331 Weiterstadt
Work Your Magic with us Ready to explore, break barriers, and discover more We know you ve got big plans - so do we Our colleagues across the globe love innovating with science and technology to enrich people s lives with our solutions in Healthcare, Life Science, and Electronics. ...
Job anzeigen
Entfalte das Besondere mit uns Sind Sie bereit, neue Wege zu gehen, Herausforderungen zu meistern und Neues zu entdecken Wir wissen, dass Sie große Pläne haben - und die haben wir auch Unsere Kolleg innen auf der ganzen Welt lieben es, mit Wissenschaft und Technologie innovativ zu sein ...
Job anzeigen
Entfalte das Besondere mit uns Sind Sie bereit, neue Wege zu gehen, Herausforderungen zu meistern und Neues zu entdecken Wir wissen, dass Sie große Pläne haben - und die haben wir auch Unsere Kolleg innen auf der ganzen Welt lieben es, mit Wissenschaft und Technologie innovativ zu sein ...
Job anzeigen
Merck
  • Sonstige
  • 25.09.2025
  • 64331 Weiterstadt
Entfalte das Besondere mit uns Sind Sie bereit, neue Wege zu gehen, Herausforderungen zu meistern und Neues zu entdecken Wir wissen, dass Sie große Pläne haben - und die haben wir auch Unsere Kolleg innen auf der ganzen Welt lieben es, mit Wissenschaft und Technologie innovativ zu sein ...
Job anzeigen
Merck
  • Sonstige
  • 24.09.2025
  • 64283 Darmstadt
Entfalte das Besondere mit uns Sind Sie bereit, neue Wege zu gehen, Herausforderungen zu meistern und Neues zu entdecken Wir wissen, dass Sie große Pläne haben - und die haben wir auch Unsere Kolleg innen auf der ganzen Welt lieben es, mit Wissenschaft und Technologie innovativ zu sein ...
Job anzeigen